Regeneration of glomerular metabolism and function by podocyte pyruvate kinase M2 in diabetic nephropathy

Diabetic nephropathy (DN) arises from systemic and local changes in glucose metabolism and hemodynamics. We have reported that many glycolytic and mitochondrial enzymes, such as pyruvate kinase M2 (PKM2), were elevated in renal glomeruli of DN-protected patients with type 1 and type 2 diabetes. Here...

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Detalles Bibliográficos
Autores principales: Fu, Jialin, Shinjo, Takanori, Li, Qian, St-Louis, Ronald, Park, Kyoungmin, Yu, Marc G., Yokomizo, Hisashi, Simao, Fabricio, Huang, Qian, Wu, I-Hsien, King, George L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983139/
https://www.ncbi.nlm.nih.gov/pubmed/35133981
http://dx.doi.org/10.1172/jci.insight.155260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983139/
https://www.ncbi.nlm.nih.gov/pubmed/35133981
http://dx.doi.org/10.1172/jci.insight.155260

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