A TCR mimic monoclonal antibody reactive with the “public” phospho-neoantigen pIRS2/HLA-A*02:01 complex

Phosphopeptides derived from dysregulated protein phosphorylation in cancer cells can be processed and presented by MHC class I and class II molecules and, therefore, represent an untapped class of tumor-specific antigens that could be used as widely expressed “public” cancer neoantigens (NeoAgs). W...

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Detalles Bibliográficos
Autores principales: Dao, Tao, Mun, Sung Soo, Molvi, Zaki, Korontsvit, Tatyana, Klatt, Martin G., Khan, Abdul G., Nyakatura, Elisabeth K., Pohl, Mary Ann, White, Thomas E., Balderes, Paul J., Lorenz, Ivo C., O’Reilly, Richard J., Scheinberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983142/
https://www.ncbi.nlm.nih.gov/pubmed/35260532
http://dx.doi.org/10.1172/jci.insight.151624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983142/
https://www.ncbi.nlm.nih.gov/pubmed/35260532
http://dx.doi.org/10.1172/jci.insight.151624

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