Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection

Severe acute lung injury has few treatment options and a high mortality rate. Upon injury, neutrophils infiltrate the lungs and form neutrophil extracellular traps (NETs), damaging the lungs and driving an exacerbated immune response. Unfortunately, no drug preventing NET formation has completed cli...

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Detalles Bibliográficos
Autores principales: Adrover, Jose M., Carrau, Lucia, Daßler-Plenker, Juliane, Bram, Yaron, Chandar, Vasuretha, Houghton, Sean, Redmond, David, Merrill, Joseph R., Shevik, Margaret, tenOever, Benjamin R., Lyons, Scott K., Schwartz, Robert E., Egeblad, Mikala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983145/
https://www.ncbi.nlm.nih.gov/pubmed/35133984
http://dx.doi.org/10.1172/jci.insight.157342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983145/
https://www.ncbi.nlm.nih.gov/pubmed/35133984
http://dx.doi.org/10.1172/jci.insight.157342

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