Aspirin Suppressed PD-L1 Expression through Suppressing KAT5 and Subsequently Inhibited PD-1 and PD-L1 Signaling to Attenuate OC Development

Ovarian cancer (OC) is a frequently occurred malignancy with high incidence and poor survival worldwide. In recent years, immune checkpoint inhibition that targets PD-1/PD-L1 axis has become an efficient and popular therapy for cancers. Aspirin (ASP), an anti-inflammatory drug, exhibits a wide spect...

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Detalles Bibliográficos
Autores principales: Xiao, Xiyun, Zeng, Saitian, Li, Yanying, Li, Lingling, Zhang, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983188/
https://www.ncbi.nlm.nih.gov/pubmed/35392432
http://dx.doi.org/10.1155/2022/4664651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983188/
https://www.ncbi.nlm.nih.gov/pubmed/35392432
http://dx.doi.org/10.1155/2022/4664651

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