α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats

The research determined the role of α-lipoic acid (ALA) in reducing the brain manifestations of insulin resistance. The mechanism of ALA action is mainly based on its ability to “scavenge” oxygen free radicals and stimulate biosynthesis of reduced glutathione (GSH), considered the most critical brai...

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Detalles Bibliográficos
Autores principales: Maciejczyk, Mateusz, Żebrowska, Ewa, Nesterowicz, Miłosz, Żendzian-Piotrowska, Małgorzata, Zalewska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983239/
https://www.ncbi.nlm.nih.gov/pubmed/35391928
http://dx.doi.org/10.1155/2022/7450514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983239/
https://www.ncbi.nlm.nih.gov/pubmed/35391928
http://dx.doi.org/10.1155/2022/7450514

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