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Decorin Protects Retinal Pigment Epithelium Cells from Oxidative Stress and Apoptosis via AMPK-mTOR-Regulated Autophagy

Age-related macular degeneration (AMD) is the leading cause of irreversible visual loss among the elderly worldwide with unidentified pathogenesis and limited therapeutic options. Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is central in the development and progression of...

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Detalles Bibliográficos
Autores principales: Xie, Xinyi, Li, Duo, Cui, Yuqing, Xie, Tianhua, Cai, Jiping, Yao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983248/
https://www.ncbi.nlm.nih.gov/pubmed/35391926
http://dx.doi.org/10.1155/2022/3955748