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Decorin Protects Retinal Pigment Epithelium Cells from Oxidative Stress and Apoptosis via AMPK-mTOR-Regulated Autophagy
Age-related macular degeneration (AMD) is the leading cause of irreversible visual loss among the elderly worldwide with unidentified pathogenesis and limited therapeutic options. Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is central in the development and progression of...
Autores principales: | Xie, Xinyi, Li, Duo, Cui, Yuqing, Xie, Tianhua, Cai, Jiping, Yao, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983248/ https://www.ncbi.nlm.nih.gov/pubmed/35391926 http://dx.doi.org/10.1155/2022/3955748 |
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