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ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats

NGF is involved in the process of autophagy; however, the underlying mechanisms of proNGF/NGF on autophagy in cerebral ischemia-reperfusion (CIR) remain unclear. This study explored the potential pathway of proNGF/NGF in mediating autophagy and apoptosis and thereby contributed to poststroke neurolo...

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Detalles Bibliográficos
Autores principales: Li, Yanbo, Wu, Fengbo, Zhou, Muke, Zhou, Jie, Cui, Shuhui, Guo, Jian, Wu, Junhao, He, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983267/
https://www.ncbi.nlm.nih.gov/pubmed/35391929
http://dx.doi.org/10.1155/2022/6098191