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Estradiol-dependent and independent effects of FGF21 in obese female mice

The f ibroblast growth factor 21 (FGF21) synthesized in the liver, acting as a hormone, increases insulin sensitivity and energy expenditure. FGF21 administration has potent benef icial effects on obesity and diabetes in humans, cynomolgus monkey, and rodents. The therapeutic effects of FGF21 have b...

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Detalles Bibliográficos
Autores principales: Jakovleva, T.V., Kazantseva, A.Yu., Dubinina, A.D., Balybina, N.Yu., Baranov, K.O., Makarova, E.N., Bazhan, N.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983308/
https://www.ncbi.nlm.nih.gov/pubmed/35434487
http://dx.doi.org/10.18699/VJGB-22-20