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Estradiol-dependent and independent effects of FGF21 in obese female mice
The f ibroblast growth factor 21 (FGF21) synthesized in the liver, acting as a hormone, increases insulin sensitivity and energy expenditure. FGF21 administration has potent benef icial effects on obesity and diabetes in humans, cynomolgus monkey, and rodents. The therapeutic effects of FGF21 have b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983308/ https://www.ncbi.nlm.nih.gov/pubmed/35434487 http://dx.doi.org/10.18699/VJGB-22-20 |