Targeting papain-like protease for broad-spectrum coronavirus inhibition

The emergence of SARS-CoV-2 variants of concern and repeated outbreaks of coronavirus epidemics in the past two decades emphasize the need for next-generation pan-coronaviral therapeutics. Drugging the multi-functional papain-like protease (PLpro) domain of the viral nsp3 holds promise. However, non...

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Detalles Bibliográficos
Autores principales: Yuan, Shuofeng, Gao, Xiaopan, Tang, Kaiming, Cai, Jian-Piao, Hu, Menglong, Luo, Peng, Wen, Lei, Ye, Zi-Wei, Luo, Cuiting, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Huang, Yaoqiang, Cao, Jianli, Liang, Ronghui, Qin, Zhenzhi, Qin, Bo, Yin, Feifei, Chu, Hin, Jin, Dong-Yan, Sun, Ren, Chan, Jasper Fuk-Woo, Cui, Sheng, Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983325/
https://www.ncbi.nlm.nih.gov/pubmed/35384604
http://dx.doi.org/10.1007/s13238-022-00909-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983325/
https://www.ncbi.nlm.nih.gov/pubmed/35384604
http://dx.doi.org/10.1007/s13238-022-00909-3

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