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KIBRA regulates amyloid β metabolism by controlling extracellular vesicles secretion

BACKGROUND: Previous research has revealed that KIBRA controls secretion of extracellular vesicles (EVs) by inhibiting the proteasomal degradation of Rab27a and EVs play an important role in amyloid β (Aβ) metabolism and transmission during Alzheimer's disease (AD) pathogenesis. Here, we furthe...

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Detalles Bibliográficos
Autores principales: Han, Xiaolei, Wang, Chaoqun, Song, Lin, Wang, Xiaojie, Tang, Shi, Hou, Tingting, Liu, Cuicui, Liang, Xiaoyan, Qiu, Chengxuan, Wang, Yongxiang, Du, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983338/
https://www.ncbi.nlm.nih.gov/pubmed/35367771
http://dx.doi.org/10.1016/j.ebiom.2022.103980