Glu(333) in rabies virus glycoprotein is involved in virus attenuation through astrocyte infection and interferon responses

The amino acid residue at position 333 of the rabies virus (RABV) glycoprotein (G333) is a major determinant of RABV pathogenicity. Virulent RABV strains possess Arg(333), whereas the attenuated strain HEP-Flury (HEP) possesses Glu(333). To investigate the potential attenuation mechanism dependent o...

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Detalles Bibliográficos
Autores principales: Itakura, Yukari, Tabata, Koshiro, Morimoto, Kohei, Ito, Naoto, Chambaro, Herman M., Eguchi, Ryota, Otsuguro, Ken-ichi, Hall, William W., Orba, Yasuko, Sawa, Hirofumi, Sasaki, Michihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983343/
https://www.ncbi.nlm.nih.gov/pubmed/35402872
http://dx.doi.org/10.1016/j.isci.2022.104122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983343/
https://www.ncbi.nlm.nih.gov/pubmed/35402872
http://dx.doi.org/10.1016/j.isci.2022.104122

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