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Regulation of Il6 expression by single CpG methylation in downstream of Il6 transcription initiation site

The innate immune system is an immediate defense against infectious pathogens by the production of inflammatory cytokines and other mediators. Deficiencies of epigenetic regulatory enzymes, such as Tet1 and Dnmt1, cause dysregulation of cytokine expression. However, it is unclear if DNA methylation...

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Detalles Bibliográficos
Autores principales: Lian, Benedict Shi Xiang, Kawasaki, Takumi, Kano, Norisuke, Ori, Daisuke, Ikegawa, Moe, Isotani, Ayako, Kawai, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983349/
https://www.ncbi.nlm.nih.gov/pubmed/35402874
http://dx.doi.org/10.1016/j.isci.2022.104118