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Regulation of Il6 expression by single CpG methylation in downstream of Il6 transcription initiation site
The innate immune system is an immediate defense against infectious pathogens by the production of inflammatory cytokines and other mediators. Deficiencies of epigenetic regulatory enzymes, such as Tet1 and Dnmt1, cause dysregulation of cytokine expression. However, it is unclear if DNA methylation...
Autores principales: | Lian, Benedict Shi Xiang, Kawasaki, Takumi, Kano, Norisuke, Ori, Daisuke, Ikegawa, Moe, Isotani, Ayako, Kawai, Taro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983349/ https://www.ncbi.nlm.nih.gov/pubmed/35402874 http://dx.doi.org/10.1016/j.isci.2022.104118 |
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