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Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates

BACKGROUND: Treatment of Blood Stream Infections (BSIs) with a combination of a β-lactam and an aminoglycoside antibiotic is widely used in intensive care units (ICUs) around the world. However, no studies have systematically examined how these drugs interact and potentially influence the antimicrob...

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Detalles Bibliográficos
Autores principales: Fatsis-Kavalopoulos, Nikos, Roelofs, Lex, Andersson, Dan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983351/
https://www.ncbi.nlm.nih.gov/pubmed/35367773
http://dx.doi.org/10.1016/j.ebiom.2022.103979