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Assessment of dopaminergic neuron degeneration in a C. elegans model of Parkinson’s disease

Transgenic Caenorhabditis elegans that expresses the full-length wild-type human α-synuclein in dopaminergic neurons provides a well-established Parkinson’s disease (PD) nematode model. Here, we present a detailed protocol to monitor and dissect the molecular underpinnings of age-associated neurodeg...

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Detalles Bibliográficos
Autores principales: Palikaras, Konstantinos, SenGupta, Tanima, Nilsen, Hilde, Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983426/
https://www.ncbi.nlm.nih.gov/pubmed/35403008
http://dx.doi.org/10.1016/j.xpro.2022.101264