Cargando…
Assessment of dopaminergic neuron degeneration in a C. elegans model of Parkinson’s disease
Transgenic Caenorhabditis elegans that expresses the full-length wild-type human α-synuclein in dopaminergic neurons provides a well-established Parkinson’s disease (PD) nematode model. Here, we present a detailed protocol to monitor and dissect the molecular underpinnings of age-associated neurodeg...
Autores principales: | Palikaras, Konstantinos, SenGupta, Tanima, Nilsen, Hilde, Tavernarakis, Nektarios |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983426/ https://www.ncbi.nlm.nih.gov/pubmed/35403008 http://dx.doi.org/10.1016/j.xpro.2022.101264 |
Ejemplares similares
-
Chemotaxis assay for evaluation of memory-like behavior in wild-type and Alzheimer’s-disease-like C. elegans models
por: Cao, Shu-qin, et al.
Publicado: (2023) -
Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology
por: SenGupta, Tanima, et al.
Publicado: (2021) -
Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging
por: SenGupta, Tanima, et al.
Publicado: (2022) -
C. elegans as an Animal Model to Study the Intersection of DNA Repair, Aging and Neurodegeneration
por: Naranjo-Galindo, Francisco José, et al.
Publicado: (2022) -
Mitophagy in neurodegeneration and aging
por: Palikaras, Konstantinos, et al.
Publicado: (2012)