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Akt-GSK3β-mPTP pathway regulates the mitochondrial dysfunction contributing to odontoblasts apoptosis induced by glucose oxidative stress

Diabetes Mellitus can cause dental pulp cells apoptosis by oxidative stress, and affect the integrity and function of dental pulp tissue. Mitochondria are the main attack targets of oxidative stress and have a critical role in apoptosis. However, whether mitochondria are involved in dental pulp dama...

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Detalles Bibliográficos
Autores principales: Wu, Danni, Yan, Liya, Zheng, Chuchu, Ren, Xuekun, Pan, Yihuai, Huang, Shengbin, Pan, Lijun, Li, Zongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983683/
https://www.ncbi.nlm.nih.gov/pubmed/35383148
http://dx.doi.org/10.1038/s41420-022-00981-y