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JAC1 targets YY1 mediated JWA/p38 MAPK signaling to inhibit proliferation and induce apoptosis in TNBC

Triple negative breast cancer (TNBC) is a type of breast cancer with poor prognosis, and has no ideal therapeutic target and ideal medicine. Downregulation of JWA is closely related to the poor overall survival in many cancers including TNBC. In this study, we reported at the first time that JWA gen...

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Detalles Bibliográficos
Autores principales: Zhai, Zurong, Ren, Yanlin, Shu, Chuanjun, Chen, Dongyin, Liu, Xia, Liang, Yan, Li, Aiping, Zhou, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983694/
https://www.ncbi.nlm.nih.gov/pubmed/35383155
http://dx.doi.org/10.1038/s41420-022-00992-9