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High-throughput translational profiling with riboPLATE-seq

Protein synthesis is dysregulated in many diseases, but we lack a systems-level picture of how signaling molecules and RNA binding proteins interact with the translational machinery, largely due to technological limitations. Here we present riboPLATE-seq, a scalable method for generating paired libr...

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Detalles Bibliográficos
Autores principales: Metz, Jordan B., Hornstein, Nicholas J., Sharma, Sohani Das, Worley, Jeremy, Gonzalez, Christian, Sims, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983706/
https://www.ncbi.nlm.nih.gov/pubmed/35383235
http://dx.doi.org/10.1038/s41598-022-09638-3