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Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation

Lipopolysaccharides are major constituents of the extracellular leaflet in the bacterial outer membrane and form an effective physical barrier for environmental threats and for antibiotics in Gram-negative bacteria. The last step of LPS insertion via the Lpt pathway is mediated by the LptD/E protein...

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Detalles Bibliográficos
Autores principales: Botte, Mathieu, Ni, Dongchun, Schenck, Stephan, Zimmermann, Iwan, Chami, Mohamed, Bocquet, Nicolas, Egloff, Pascal, Bucher, Denis, Trabuco, Matilde, Cheng, Robert K. Y., Brunner, Janine D., Seeger, Markus A., Stahlberg, Henning, Hennig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983717/
https://www.ncbi.nlm.nih.gov/pubmed/35383177
http://dx.doi.org/10.1038/s41467-022-29459-2