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DUB3/KLF4 combats tumor growth and chemoresistance in hepatocellular carcinoma

This study aimed to investigate the role of deubiquitinating enzyme 3 (DUB3) in the regulation of Krüppel-like factor 4 (KLF4) expression in hepatocellular carcinoma (HCC). Gain- and loss-of-function assay, luciferase reporter assay, co-immunoprecipitation, and intracellular and extracellular deubiq...

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Detalles Bibliográficos
Autores principales: Jia, Xuebing, Li, Lei, Wang, Fan, Xue, Ying, Wu, Tongde, Jia, Qianqian, Li, Yunhui, Wu, Chenming, Chen, Yuping, Wu, Jinhuan, Su, Yang, Wang, Xinshu, Zhuang, Tao, Dong, Xiao, Ling, Jing, Yuan, Jian, Li, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983766/
https://www.ncbi.nlm.nih.gov/pubmed/35383144
http://dx.doi.org/10.1038/s41420-022-00988-5