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A novel process driving Alzheimer's disease validated in a mouse model: Therapeutic potential
INTRODUCTION: The neuronal mechanism driving Alzheimer's disease (AD) is incompletely understood. METHODS: Immunohistochemistry, pharmacology, biochemistry, and behavioral testing are employed in two pathological contexts—AD and a transgenic mouse model—to investigate T14, a 14mer peptide, as a...
Autores principales: | Greenfield, Susan A., Cole, Gregory M., Coen, Clive W., Frautschy, Sally, Singh, Ram P., Mekkittikul, Marisa, Garcia‐Ratés, Sara, Morrill, Paul, Hollings, Owen, Passmore, Matt, Hasan, Sibah, Carty, Nikisha, Bison, Silvia, Piccoli, Laura, Carletti, Renzo, Tacconi, Stephano, Chalidou, Anna, Pedercini, Matthew, Kroecher, Tim, Astner, Hubert, Gerrard, Philip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983808/ https://www.ncbi.nlm.nih.gov/pubmed/35415206 http://dx.doi.org/10.1002/trc2.12274 |
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