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Electrophysiological Properties of Induced Pluripotent Stem Cell-Derived Midbrain Dopaminergic Neurons Correlate With Expression of Tyrosine Hydroxylase

Induced pluripotent stem cell (iPSC)-based generation of tyrosine hydroxylase-positive (TH(+)) dopaminergic neurons (DNs) is a powerful method for creating patient-specific in vitro models to elucidate mechanisms underlying Parkinson’s disease (PD) at the cellular and molecular level and to perform...

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Detalles Bibliográficos
Autores principales: Rakovic, Aleksandar, Voß, Dorothea, Vulinovic, Franca, Meier, Britta, Hellberg, Ann-Katrin, Nau, Carla, Klein, Christine, Leipold, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983830/
https://www.ncbi.nlm.nih.gov/pubmed/35401116
http://dx.doi.org/10.3389/fncel.2022.817198