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Lipophosphoglycan From Dermotropic New World Leishmania Upregulates Interleukin-32 and Proinflammatory Cytokines Through TLR4 and NOD2 Receptors

Interleukin-32 (IL-32) is produced during Leishmania infection, but the components of the parasite that induce its production are unknown. An important multivirulence factor of Leishmania spp. protozoa is the lipophosphoglycan (LPG), which plays a crucial role in the host-parasite interaction. Here,...

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Detalles Bibliográficos
Autores principales: Silveira, Murilo Barros, Gomes, Rodrigo Saar, Shio, Marina Tiemi, Rugani, Jeronimo Nunes, Paranaiba, Larissa Ferreira, Soares, Rodrigo Pedro, Ribeiro-Dias, Fátima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983857/
https://www.ncbi.nlm.nih.gov/pubmed/35402314
http://dx.doi.org/10.3389/fcimb.2022.805720