Cargando…
Lipophosphoglycan From Dermotropic New World Leishmania Upregulates Interleukin-32 and Proinflammatory Cytokines Through TLR4 and NOD2 Receptors
Interleukin-32 (IL-32) is produced during Leishmania infection, but the components of the parasite that induce its production are unknown. An important multivirulence factor of Leishmania spp. protozoa is the lipophosphoglycan (LPG), which plays a crucial role in the host-parasite interaction. Here,...
Autores principales: | Silveira, Murilo Barros, Gomes, Rodrigo Saar, Shio, Marina Tiemi, Rugani, Jeronimo Nunes, Paranaiba, Larissa Ferreira, Soares, Rodrigo Pedro, Ribeiro-Dias, Fátima |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983857/ https://www.ncbi.nlm.nih.gov/pubmed/35402314 http://dx.doi.org/10.3389/fcimb.2022.805720 |
Ejemplares similares
-
Lipophosphoglycans from dermotropic Leishmania
infantum are more pro-inflammatory than those from viscerotropic
strains
por: Cardoso, Camila A, et al.
Publicado: (2020) -
Intraspecies Polymorphisms in the Lipophosphoglycan of L. braziliensis Differentially Modulate Macrophage Activation via TLR4
por: Vieira, Tamara da Silva, et al.
Publicado: (2019) -
Leishmania enriettii: biochemical characterisation of lipophosphoglycans (LPGs) and glycoinositolphospholipids (GIPLs) and infectivity to Cavia porcellus
por: Paranaíba, Larissa Ferreira, et al.
Publicado: (2015) -
Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection
por: Nogueira, Paula M., et al.
Publicado: (2016) -
Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome
por: de Carvalho, Renan V.H., et al.
Publicado: (2019)