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Repeated Lineage Switches in an Elderly Case of Refractory B-Cell Acute Lymphoblastic Leukemia With MLL Gene Amplification: A Case Report and Literature Review

Lineage switches in acute leukemia occur rarely, and the underlying mechanisms are poorly understood. Herein, we report the case of an elderly patient with leukemia in which the leukemia started as B-cell acute lymphoblastic leukemia (B-ALL) and later changed to B- and T-cell mixed phenotype acute l...

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Detalles Bibliográficos
Autores principales: Takeda, Reina, Yokoyama, Kazuaki, Fukuyama, Tomofusa, Kawamata, Toyotaka, Ito, Mika, Yusa, Nozomi, Kasajima, Rika, Shimizu, Eigo, Ohno, Nobuhiro, Uchimaru, Kaoru, Yamaguchi, Rui, Imoto, Seiya, Miyano, Satoru, Tojo, Arinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983914/
https://www.ncbi.nlm.nih.gov/pubmed/35402256
http://dx.doi.org/10.3389/fonc.2022.799982