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Repeated Lineage Switches in an Elderly Case of Refractory B-Cell Acute Lymphoblastic Leukemia With MLL Gene Amplification: A Case Report and Literature Review
Lineage switches in acute leukemia occur rarely, and the underlying mechanisms are poorly understood. Herein, we report the case of an elderly patient with leukemia in which the leukemia started as B-cell acute lymphoblastic leukemia (B-ALL) and later changed to B- and T-cell mixed phenotype acute l...
Autores principales: | Takeda, Reina, Yokoyama, Kazuaki, Fukuyama, Tomofusa, Kawamata, Toyotaka, Ito, Mika, Yusa, Nozomi, Kasajima, Rika, Shimizu, Eigo, Ohno, Nobuhiro, Uchimaru, Kaoru, Yamaguchi, Rui, Imoto, Seiya, Miyano, Satoru, Tojo, Arinobu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983914/ https://www.ncbi.nlm.nih.gov/pubmed/35402256 http://dx.doi.org/10.3389/fonc.2022.799982 |
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