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Hesperetin Inhibits Sphingosylphosphorylcholine-Induced Vascular Smooth Muscle Contraction by Regulating the Fyn/Rho-Kinase Pathway

Cardiovascular diseases are the leading cause of mortality and disability worldwide. We have previously found that sphingosylphosphorylcholine (SPC) is the key molecule leading to vasospasm. We have also identified the SPC/Src family protein tyrosine kinase Fyn/Rho-kinase (ROK) pathway as a novel si...

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Detalles Bibliográficos
Autores principales: Lu, Qian, Kishi, Hiroko, Zhang, Ying, Morita, Tomoka, Kobayashi, Sei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983948/
https://www.ncbi.nlm.nih.gov/pubmed/34983908
http://dx.doi.org/10.1097/FJC.0000000000001210