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Growth arrest of PPP2R5C and PPP2R5D double knockout mice indicates a genetic interaction and conserved function for these PP2A B subunits

Protein phosphatase 2A (PP2A) is a heterotrimeric phosphatase that controls a wide range of cellular functions. The catalytic activity and intracellular location of PP2A are modulated by its association with regulatory B subunits, including B56 proteins, which are encoded by five separate genes in h...

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Detalles Bibliográficos
Autores principales: Dyson, Jade J., Abbasi, Fatima, Varadkar, Prajakta, McCright, Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984082/
https://www.ncbi.nlm.nih.gov/pubmed/35415460
http://dx.doi.org/10.1096/fba.2021-00130