Machine learning methods applied to genotyping data capture interactions between single nucleotide variants in late onset Alzheimer's disease

INTRODUCTION: Genome‐wide association studies (GWAS) in late onset Alzheimer's disease (LOAD) provide lists of individual genetic determinants. However, GWAS do not capture the synergistic effects among multiple genetic variants and lack good specificity. METHODS: We applied tree‐based machine...

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Detalles Bibliográficos
Autores principales: Arnal Segura, Magdalena, Bini, Giorgio, Fernandez Orth, Dietmar, Samaras, Eleftherios, Kassis, Maya, Aisopos, Fotis, Rambla De Argila, Jordi, Paliouras, George, Garrard, Peter, Giambartolomei, Claudia, Tartaglia, Gian Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984091/
https://www.ncbi.nlm.nih.gov/pubmed/35415203
http://dx.doi.org/10.1002/dad2.12300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984091/
https://www.ncbi.nlm.nih.gov/pubmed/35415203
http://dx.doi.org/10.1002/dad2.12300

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