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Plasma p217+tau versus NAV4694 amyloid and MK6240 tau PET across the Alzheimer's continuum

INTRODUCTION: We evaluated a new Simoa plasma assay for phosphorylated tau (P‐tau) at aa217 enhanced by additional p‐tau sites (p217+tau). METHODS: Plasma p217+tau levels were compared to (18)F‐NAV4694 amyloid beta (Aβ) positron emission tomography (PET) and (18)F‐MK6240 tau PET in 174 cognitively i...

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Detalles Bibliográficos
Autores principales: Doré, Vincent, Doecke, James D., Saad, Ziad S., Triana‐Baltzer, Gallen, Slemmon, Randy, Krishnadas, Natasha, Bourgeat, Pierrick, Huang, Kun, Burnham, Samantha, Fowler, Christopher, Rainey‐Smith, Stephanie R., Bush, Ashley I., Ward, Larry, Robertson, Jo, Martins, Ralph N., Masters, Colin L., Villemagne, Victor L., Fripp, Jurgen, Kolb, Hartmuth C., Rowe, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984092/
https://www.ncbi.nlm.nih.gov/pubmed/35415202
http://dx.doi.org/10.1002/dad2.12307