Cargando…

Proportional constrained longitudinal data analysis models for clinical trials in sporadic Alzheimer's disease

INTRODUCTION: Clinical trials for sporadic Alzheimer's disease generally use mixed models for repeated measures (MMRM) or, to a lesser degree, constrained longitudinal data analysis models (cLDA) as the analysis model with time since baseline as a categorical variable. Inferences using MMRM/cLD...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Guoqiao, Liu, Lei, Li, Yan, Aschenbrenner, Andrew J., Bateman, Randall J., Delmar, Paul, Schneider, Lon S., Kennedy, Richard E., Cutter, Gary R., Xiong, Chengjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984094/
https://www.ncbi.nlm.nih.gov/pubmed/35415211
http://dx.doi.org/10.1002/trc2.12286