PA1 cells containing a truncated DNA polymerase β protein are more sensitive to gamma radiation

PURPOSE: DNA polymerase β (Polβ) acts in the base excision repair (BER) pathway. Mutations in DNA polymerase β (Polβ) are associated with different cancers. A variant of Polβ with a 97 amino acid deletion (PolβΔ), in heterozygous conditions with wild-type Polβ, was identified in sporadic ovarian tum...

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Detalles Bibliográficos
Autores principales: Patra, Anutosh, Nag, Anish, Chakraborty, Anindita, Bhattacharyya, Nandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Radiation Oncology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984132/
https://www.ncbi.nlm.nih.gov/pubmed/35368202
http://dx.doi.org/10.3857/roj.2021.00689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984132/
https://www.ncbi.nlm.nih.gov/pubmed/35368202
http://dx.doi.org/10.3857/roj.2021.00689

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