PIK3CA Mutations Drive Therapeutic Resistance in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

The phosphatidylinositol 3-kinase (PI3K) pathway is an intracellular pathway activated in response to progrowth signaling, such as human epidermal growth factor receptor 2 (HER2) and other kinases. Abnormal activation of PI3K has long been recognized as one of the main oncogenic drivers in breast ca...

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Detalles Bibliográficos
Autores principales: Rasti, Aryana R., Guimaraes-Young, Amy, Datko, Farrah, Borges, Virginia F., Aisner, Dara L., Shagisultanova, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
REVIEW ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984255/
https://www.ncbi.nlm.nih.gov/pubmed/35357905
http://dx.doi.org/10.1200/PO.21.00370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984255/
https://www.ncbi.nlm.nih.gov/pubmed/35357905
http://dx.doi.org/10.1200/PO.21.00370

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