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GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration

Human immunodeficiency virus type 1 (HIV-1) is known to provoke microglial immune responses which likely play a paramount role in the development of chronic neuroinflammatory conditions and neuronal damage related to HIV-1 associated neurocognitive disorders (HAND). In particular, HIV-1 Tat protein...

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Detalles Bibliográficos
Autores principales: Hermes, Douglas J., Yadav-Samudrala, Barkha J., Xu, Changqing, Paniccia, Jacqueline E., Meeker, Rick B., Armstrong, Michael L., Reisdorph, Nichole, Cravatt, Benjamin F., Mackie, Ken, Lichtman, Aron H., Ignatowska-Jankowska, Bogna M., Lysle, Donald T., Fitting, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984429/
https://www.ncbi.nlm.nih.gov/pubmed/33736974
http://dx.doi.org/10.1016/j.expneurol.2021.113699