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Effectiveness and Safety of Niraparib as Neoadjuvant Therapy in Advanced Ovarian Cancer With Homologous Recombination Deficiency (NANT): Study Protocol for a Prospective, Multicenter, Exploratory, Phase 2, Single-Arm Study

BACKGROUND: Ovarian cancer (OC) is a heterogeneous gynecological malignancy with a poor prognosis as the majority of patients are diagnosed at an advanced stage. Neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) is recommended for patients who cannot achieve optimal cytore...

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Detalles Bibliográficos
Autores principales: Zhou, Dongchen, Liu, Jiahao, Liu, Ronghua, Li, Huayi, Huang, Yi, Ma, Ding, Hong, Li, Gao, Qinglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984467/
https://www.ncbi.nlm.nih.gov/pubmed/35402241
http://dx.doi.org/10.3389/fonc.2022.852772