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Escaping Death: How Cancer Cells and Infected Cells Resist Cell-Mediated Cytotoxicity

Cytotoxic lymphocytes are critical in our immune defence against cancer and infection. Cytotoxic T lymphocytes and Natural Killer cells can directly lyse malignant or infected cells in at least two ways: granule-mediated cytotoxicity, involving perforin and granzyme B, or death receptor-mediated cyt...

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Detalles Bibliográficos
Autores principales: Tuomela, Karoliina, Ambrose, Ashley R., Davis, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984481/
https://www.ncbi.nlm.nih.gov/pubmed/35401556
http://dx.doi.org/10.3389/fimmu.2022.867098