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Escaping Death: How Cancer Cells and Infected Cells Resist Cell-Mediated Cytotoxicity
Cytotoxic lymphocytes are critical in our immune defence against cancer and infection. Cytotoxic T lymphocytes and Natural Killer cells can directly lyse malignant or infected cells in at least two ways: granule-mediated cytotoxicity, involving perforin and granzyme B, or death receptor-mediated cyt...
Autores principales: | Tuomela, Karoliina, Ambrose, Ashley R., Davis, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984481/ https://www.ncbi.nlm.nih.gov/pubmed/35401556 http://dx.doi.org/10.3389/fimmu.2022.867098 |
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