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The Age-Driven Decline in Neutrophil Function Contributes to the Reduced Efficacy of the Pneumococcal Conjugate Vaccine in Old Hosts

Despite the availability of vaccines, Streptococcus pneumoniae (pneumococcus) remains a serious cause of infections in the elderly. The efficacy of anti-pneumococcal vaccines declines with age. While age-driven changes in antibody responses are well defined, less is known about the role of innate im...

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Detalles Bibliográficos
Autores principales: Simmons, Shaunna R., Tchalla, Essi Y. I., Bhalla, Manmeet, Bou Ghanem, Elsa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984502/
https://www.ncbi.nlm.nih.gov/pubmed/35402289
http://dx.doi.org/10.3389/fcimb.2022.849224