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Three-component microwave-assisted synthesis of 3,5-disubstituted pyrazolo[3,4-d]pyrimidin-4-ones

A practical three-component method for the synthesis of pyrazolo[3,4-d]pyrimidin-4-ones was developed. The reaction was performed in a one-pot manner under controlled microwave irradiation using easily accessible methyl 5-aminopyrazole-4-carboxylates, trimethyl orthoformate, and primary amines. Unde...

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Detalles Bibliográficos
Autores principales: Ng, Jia Hui, Tiekink, Edward R. T., Dolzhenko, Anton V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984946/
https://www.ncbi.nlm.nih.gov/pubmed/35424837
http://dx.doi.org/10.1039/d2ra00980c