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Synthesis of chiral sulfinate esters by asymmetric condensation
Achiral sulfur functional groups, such as sulfonamide, sulfone, thiol and thioether, are common in drugs and natural products. By contrast, chiral sulfur functional groups are often neglected as pharmacophores(1–3), although sulfoximine, with its unique physicochemical and pharmacokinetic properties...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985065/ https://www.ncbi.nlm.nih.gov/pubmed/35158370 http://dx.doi.org/10.1038/s41586-022-04524-4 |