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Synthesis of chiral sulfinate esters by asymmetric condensation

Achiral sulfur functional groups, such as sulfonamide, sulfone, thiol and thioether, are common in drugs and natural products. By contrast, chiral sulfur functional groups are often neglected as pharmacophores(1–3), although sulfoximine, with its unique physicochemical and pharmacokinetic properties...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Ang, Esther Cai Xia, Yang, Ziqi, Kee, Choon Wee, Tan, Choon-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985065/
https://www.ncbi.nlm.nih.gov/pubmed/35158370
http://dx.doi.org/10.1038/s41586-022-04524-4