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Bromo-lactamization of isoxazole via neighboring group participation: toward spiro-isoxazoline γ- and δ-lactams

Spiro-heterocycles containing natural products and synthetic analogues have a broader biomedicinal application due to their rigid 3D conformation and structural implications. In this context, constructing spiro-isoxazoline systems have continued our interest in natural products and synthetic units t...

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Detalles Bibliográficos
Autores principales: Das, Prasanta, Carter, Cord, Shaheen, Gulrukh, Hamme, Ashton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985116/
https://www.ncbi.nlm.nih.gov/pubmed/35424956
http://dx.doi.org/10.1039/d2ra01070d