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Cardiac Xenotransplantation: Progress in Preclinical Models and Prospects for Clinical Translation

Survival of pig cardiac xenografts in a non-human primate (NHP) model has improved significantly over the last 4 years with the introduction of costimulation blockade based immunosuppression (IS) and genetically engineered (GE) pig donors. The longest survival of a cardiac xenograft in the heterotop...

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Detalles Bibliográficos
Autores principales: Singh, Avneesh K., Goerlich, Corbin E., Shah, Aakash M., Zhang, Tianshu, Tatarov, Ivan, Ayares, David, Horvath, Keith A., Mohiuddin, Muhammad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985160/
https://www.ncbi.nlm.nih.gov/pubmed/35401039
http://dx.doi.org/10.3389/ti.2022.10171