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Salvianolic acid B acts against non-small cell lung cancer A549 cells via inactivation of the MAPK and Smad2/3 signaling pathways

Salvianolic acid B (Sal B) is a potential cytotoxic polyphenol against cancer. In the present study the effect of Sal B and its molecular mechanism were investigated in the non-small cell lung cancer (NSCLC) A549 cell line. The TGF-β/MAPK/Smad signaling axis was explored. A549 cells were co-cultured...

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Detalles Bibliográficos
Autores principales: Han, Guanglei, Wang, Yongzhong, Liu, Tong, Gao, Jiarong, Duan, Fengyi, Chen, Ming, Yang, Yan, Wu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985201/
https://www.ncbi.nlm.nih.gov/pubmed/35348194
http://dx.doi.org/10.3892/mmr.2022.12700