Conserved and divergent features of neuronal CaMKII holoenzyme structure, function, and high-order assembly

Neuronal CaMKII holoenzymes (α and β isoforms) enable molecular signal computation underlying learning and memory but also mediate excitotoxic neuronal death. Here, we provide a comparative analysis of these signaling devices, using single-particle electron microscopy (EM) in combination with bioche...

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Detalles Bibliográficos
Autores principales: Buonarati, Olivia R., Miller, Adam P., Coultrap, Steven J., Bayer, K. Ulrich, Reichow, Steve L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985225/
https://www.ncbi.nlm.nih.gov/pubmed/34965414
http://dx.doi.org/10.1016/j.celrep.2021.110168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985225/
https://www.ncbi.nlm.nih.gov/pubmed/34965414
http://dx.doi.org/10.1016/j.celrep.2021.110168

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