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Conserved and divergent features of neuronal CaMKII holoenzyme structure, function, and high-order assembly
Neuronal CaMKII holoenzymes (α and β isoforms) enable molecular signal computation underlying learning and memory but also mediate excitotoxic neuronal death. Here, we provide a comparative analysis of these signaling devices, using single-particle electron microscopy (EM) in combination with bioche...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985225/ https://www.ncbi.nlm.nih.gov/pubmed/34965414 http://dx.doi.org/10.1016/j.celrep.2021.110168 |