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Targeting selenoprotein H in the nucleolus suppresses tumors and metastases by Isovalerylspiramycin I
BACKGROUND: Compared to normal cells, cancer cells exhibit a higher level of oxidative stress, which primes key cellular and metabolic pathways and thereby increases their resilience under oxidative stress. This higher level of oxidative stress also can be exploited to kill tumor cells while leaving...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985259/ https://www.ncbi.nlm.nih.gov/pubmed/35387667 http://dx.doi.org/10.1186/s13046-022-02350-0 |