Targeting selenoprotein H in the nucleolus suppresses tumors and metastases by Isovalerylspiramycin I

BACKGROUND: Compared to normal cells, cancer cells exhibit a higher level of oxidative stress, which primes key cellular and metabolic pathways and thereby increases their resilience under oxidative stress. This higher level of oxidative stress also can be exploited to kill tumor cells while leaving...

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Detalles Bibliográficos
Autores principales: Cui, Jing, Zhou, Jingcheng, He, Weiqing, Ye, Juan, Westlake, Timothy, Medina, Rogelio, Wang, Herui, Thakur, Bhushan L., Liu, Juanjuan, Xia, Mingyu, He, Zhonggui, Indig, Fred E., Li, Aiguo, Li, Yan, Weil, Robert J., Aladjem, Mirit I., Zhong, Laiping, Gilbert, Mark R., Zhuang, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985259/
https://www.ncbi.nlm.nih.gov/pubmed/35387667
http://dx.doi.org/10.1186/s13046-022-02350-0

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