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Investigating treatment-effect modification by a continuous covariate in IPD meta-analysis: an approach using fractional polynomials
BACKGROUND: In clinical trials, there is considerable interest in investigating whether a treatment effect is similar in all patients, or that one or more prognostic variables indicate a differential response to treatment. To examine this, a continuous predictor is usually categorised into groups ac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985287/ https://www.ncbi.nlm.nih.gov/pubmed/35382744 http://dx.doi.org/10.1186/s12874-022-01516-w |